Tumor classification hierarchy
Differentiation state
Embryonic origin
Biological behavior
DIFFERENTIATION STATE I – EPITHELIAL CANCERS
| Embryonic derivation Ectoderm | Embryonic derivation Endoderm | Embryonic derivation Mesoderm |
| Bilayer epithelium | Single-layer epithelium | Single-layer epithelium |
| Cell type breast sweat glands salivary glands Bening adenoma Malignant adenocarcinoma | Cell type thyroid lung stomach liver pancreas small intestine colon prostate Bening adenoma Malignant adenocarcinoma | Cell type kidney testis endometrium Bening adenoma Malignant adenocarcinoma |
| Multi-layered epithelium | Multi-layered epithelium | |
| Cell type skin keratinocytes Bening papilloma Malignant squamous cell carcinoma | Cell type bladder Bening papilloma Malignant transitional cell carcinoma | |